• DOI:10.1002/cbdv.201300376
• Corpus ID: 32468225

Secondary Metabolites of Plants from the Genus Chloranthus: Chemistry and Biological Activities

@article{Wang2015SecondaryMO,
  title={Secondary Metabolites of Plants from the Genus Chloranthus: Chemistry and Biological Activities},
  author={An-ran Wang and Hongchuan Song and Hongmei An and Qian Huang and Xie Luo and Jinyan Dong},
  journal={Chemistry \& Biodiversity},
  year={2015},
  volume={12}
}

• An-ran Wang, Hongchuan Song, +3 authors Jinyan Dong
• Published 1 April 2015
• Chemistry, Biology
• Chemistry & Biodiversity

Chloranthus, a genus of the family Chloranthaceae, which is mainly distributed in eastern and southern Asia, has been used in Chinese folk medicine due to its antitumor, antifungal, and anti‐inflammatory activities. This review compiles the research on isolation, structure elucidation, structural diversity, and bioactivities of Chloranthus secondary metabolites reported between 2007 and 2013. The metabolites listed encompass 82 sesquiterpenoids, 50 dimeric sesquiterpenoids, 15 diterpenoids, one coumarin, and five other compounds. Among them, dimeric sesquiterpenoids, the characteristic components of plants from the genus Chloranthus, have attracted considerable attention due to their complex structures and significant biological features, e.g., antitumor, antibacterial, antifungal, anti‐inflammatory, and hepatoprotective activities, and potent and selective inhibition of the delayed rectifier (IK) K+ current and tyrosinase.