Secondary Hyperparathyroidism in End-Stage Renal Disease: No Longer a Matter for Surgeons?

@article{Cozzolino2016SecondaryHI,
  title={Secondary Hyperparathyroidism in End-Stage Renal Disease: No Longer a Matter for Surgeons?},
  author={Mario Gennaro Cozzolino and Francesca Marta Elli and Stefano Carugo and Paola Ciceri},
  journal={Blood purification},
  year={2016},
  volume={42 1},
  pages={44-8}
}
Hyperphosphatemia, hypocalcemia and vitamin D deficiency are the main factors involved in the pathogenesis of secondary hyperparathyroidism (SHPT). Moreover, the skeletal resistance to parathyroid hormone is not only a high-turnover bone accompanying SHPT, but may also play a crucial role in the onset of low-turnover bone disease in uremia. However, a growing body of evidence suggests that other hormones play a key role in this disease, such as fibroblast growth factor 23, Klotho and sclerostin… CONTINUE READING