Secondary Hemophagocytic Lymphohistiocytosis (HLH) from a Presumed Brown Recluse Spider Bite

Abstract

Systemic loxoscelism is a rare complication after Loxosceles reclusa (brown recluse spider) envenomation. Loxosceles venom contains pro-inflammatory proteins, which have been shown to be elevated in patients with hemophagocytic lymph histiocytosis. We present a case of a 10-year-old male that developed presumed systemic loxoscelism, secondary hemophagocytic lymphohistiocytosis with hepatic dysfunction and renal failure. He was treated with dexamethasone and made a full recovery.

DOI: 10.1007/s10875-014-0036-1

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@article{Dandoy2014SecondaryHL, title={Secondary Hemophagocytic Lymphohistiocytosis (HLH) from a Presumed Brown Recluse Spider Bite}, author={Christopher Dandoy and Michael Grimley}, journal={Journal of Clinical Immunology}, year={2014}, volume={34}, pages={544-547} }