Second-trimester genetic sonography in patients with advanced maternal age and normal triple screen.

@article{Vintzileos2002SecondtrimesterGS,
  title={Second-trimester genetic sonography in patients with advanced maternal age and normal triple screen.},
  author={Anthony M. Vintzileos and Edwin R. Guzman and John C. Smulian and Lami Yeo and William E. Scorza and Robert A. Knuppel},
  journal={Obstetrics and gynecology},
  year={2002},
  volume={99 6},
  pages={993-5}
}
OBJECTIVE To estimate the value of second-trimester genetic sonography in detecting fetal Down syndrome in patients with advanced maternal age (at least 35 years) and normal triple screen. METHODS Since July 1999, a prospective collection and recording of all individual triple screen risks for fetal Down syndrome was initiated for all patients with advanced maternal age presenting in our ultrasound unit for second-trimester genetic sonography. Genetic sonography evaluated the presence or… CONTINUE READING

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