Second solid cancers after radiation therapy: a systematic review of the epidemiologic studies of the radiation dose-response relationship.

@article{Gonzlez2013SecondSC,
  title={Second solid cancers after radiation therapy: a systematic review of the epidemiologic studies of the radiation dose-response relationship.},
  author={Amy Berrington de Gonz{\'a}lez and Ethel Gilbert and Rochelle E. Curtis and Peter D. Inskip and Ruth A. Kleinerman and Lindsay McOmber Morton and Preetha Rajaraman and Mark P. Little},
  journal={International journal of radiation oncology, biology, physics},
  year={2013},
  volume={86 2},
  pages={
          224-33
        }
}
Rapid innovations in radiation therapy techniques have resulted in an urgent need for risk projection models for second cancer risks from high-dose radiation exposure, because direct observation of the late effects of newer treatments will require patient follow-up for a decade or more. However, the patterns of cancer risk after fractionated high-dose radiation are much less well understood than those after lower-dose exposures (0.1-5 Gy). In particular, there is uncertainty about the shape of… CONTINUE READING
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