Second messengers, ion channels and pharmacology of airway smooth muscle.

@article{Hall2000SecondMI,
  title={Second messengers, ion channels and pharmacology of airway smooth muscle.},
  author={Ian P Hall},
  journal={The European respiratory journal},
  year={2000},
  volume={15 6},
  pages={1120-7}
}
  • Ian P Hall
  • Published 2000 in The European respiratory journal
The airway smooth muscle cell is the chief effector cell governing the control of airway calibre in the human lung. The contractile state of the airway smooth muscle cell is predominantly influenced by the balance of constrictor and relaxant stimuli. Agents such as histamine and acetylcholine cause airway smooth muscle cells to contract through activation of specific cell surface receptors and engagement of signal transduction pathways and/or ion channels. The predominant pathway mediating… CONTINUE READING