Second-line therapy for advanced pancreatic cancer: a review of the literature and future directions.

@article{Custodio2009SecondlineTF,
  title={Second-line therapy for advanced pancreatic cancer: a review of the literature and future directions.},
  author={Ana Bel{\'e}n Custodio and Javier Puente and Javier M. Sastre and Eduardo Diaz-Rubio},
  journal={Cancer treatment reviews},
  year={2009},
  volume={35 8},
  pages={676-84}
}
Whereas first-line chemotherapy (CT) with single-agent gemcitabine or gemcitabine-based combinations provides a proven benefit in patients with locally advanced or metastatic pancreatic cancer (PC), the role of salvage CT after gemcitabine-failure is not well-established and to date no regimen has emerged as preferred in this setting. Several clinical… CONTINUE READING