Second harmonic generation microscopy reveals altered collagen microstructure in usual interstitial pneumonia versus healthy lung

@inproceedings{Kottmann2015SecondHG,
  title={Second harmonic generation microscopy reveals altered collagen microstructure in usual interstitial pneumonia versus healthy lung},
  author={Robert Matthew Kottmann and Jesse Wakefield Sharp and Kristina M. Owens and Peter Jay Salzman and Guang-Qian Xiao and Richard P Phipps and Patricia J. Sime and Edward Bernard Brown and Seth W. Perry},
  booktitle={Respiratory research},
  year={2015}
}
BACKGROUND It is not understood why some pulmonary fibroses such as cryptogenic organizing pneumonia (COP) respond well to treatment, while others like usual interstitial pneumonia (UIP) do not. Increased understanding of the structure and function of the matrix in this area is critical to improving our understanding of the biology of these diseases and developing novel therapies. The objectives herein are to provide new insights into the underlying collagen- and matrix-related biological… CONTINUE READING
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