Second allogeneic hematopoietic SCT for relapsed ALL in children

@article{Kato2012SecondAH,
  title={Second allogeneic hematopoietic SCT for relapsed ALL in children},
  author={Motohiro Kato and Yasuo Horikoshi and Yuki Okamoto and Yoshiyuki Takahashi and Daiichiro Hasegawa and Katsuyoshi Koh and Junko Takita and Masami Inoue and Hisato Kigasawa and Atsushi Ogawa and Youji Sasahara and Keisei Kawa and Hiromasa Yabe and Hisashi Sakamaki and Ritsuro Suzuki and Koji Kato},
  journal={Bone Marrow Transplantation},
  year={2012},
  volume={47},
  pages={1307-1311}
}
A second SCT is generally accepted as the only potentially curative approach for ALL patients that relapse after SCT, but the role of second SCT for pediatric ALL is not fully understood. We performed a retrospective analysis of 171 pediatric patients who received a second allo-SCT for relapsed ALL after allo-SCT. OS at 2 years was 29.4±3.7%, the cumulative incidence of relapse was 44.1±4.0% and non-relapse mortality was 18.8±3.5%. Relapse occurred faster after the second SCT than after the… CONTINUE READING
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