Second Generation Drug-Eluting Stents: A Review of the Everolimus-Eluting Platform

@article{Whitbeck2013SecondGD,
  title={Second Generation Drug-Eluting Stents: A Review of the Everolimus-Eluting Platform},
  author={M. Whitbeck and R. Applegate},
  journal={Clinical Medicine Insights. Cardiology},
  year={2013},
  volume={7},
  pages={115 - 126}
}
Everolimus-eluting stents (EES) represent the next generation of drug-eluting stents (DES). Important design modifications include thin strut stent backbones, less inflammatory and more biocompatible polymers, and lower drug dosing. The cobalt chromium EES fluoropolymer XIENCE V stent has been the most extensively studied of such stents. In animal models, this stent demonstrated minimal vessel inflammation, a biologically active endothelium with strut coverage similar to a bare metal stent, and… Expand
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