Second-Generation Antipsychotics and Metabolic Side Effects: A Systematic Review of Population-Based Studies.

@article{Hirsch2017SecondGenerationAA,
  title={Second-Generation Antipsychotics and Metabolic Side Effects: A Systematic Review of Population-Based Studies.},
  author={Lauren Hirsch and Jaeun Jane Yang and Lauren C. Bresee and Nathalie Jette and Scott B Patten and Tamara Pringsheim},
  journal={Drug safety},
  year={2017},
  volume={40 9},
  pages={
          771-781
        }
}
INTRODUCTION There is strong evidence from randomized controlled trials (RCTs) that second-generation antipsychotic (SGA) medications are associated with metabolic adverse events. However, with the recent increases in the use of SGAs worldwide and frequent off-label use, it is unclear whether these associations are generalizable to populations beyond those included in RCTs. OBJECTIVES This review aims to characterize the impact of SGAs on the population through a systematic review of… CONTINUE READING
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Cochrane Handbook for Systematic Reviews of Interventions

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2006
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