SecA, a remarkable nanomachine

  title={SecA, a remarkable nanomachine},
  author={Ilja Kusters and Arnold J M Driessen},
  booktitle={Cellular and Molecular Life Sciences},
Biological cells harbor a variety of molecular machines that carry out mechanical work at the nanoscale. One of these nanomachines is the bacterial motor protein SecA which translocates secretory proteins through the protein-conducting membrane channel SecYEG. SecA converts chemically stored energy in the form of ATP into a mechanical force to drive polypeptide transport through SecYEG and across the cytoplasmic membrane. In order to accommodate a translocating polypeptide chain and to release… CONTINUE READING
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Identification of two interac- tion sites in SecY that are important for the functional interaction with SecA

  • EO van der Sluis, N Nouwen, +4 authors AJ Driessen
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