Sec16p potentiates the action of COPII proteins to bud transport vesicles

Abstract

SEC16 encodes a 240-kD hydrophilic protein that is required for transport vesicle budding from the ER in Saccharomyces cerevisiae. Sec16p is tightly and peripherally bound to ER membranes, hence it is not one of the cytosolic proteins required to reconstitute transport vesicle budding in a cell-free reaction. However, Sec16p is removed from the membrane by… (More)

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@article{Supek2002Sec16pPT, title={Sec16p potentiates the action of COPII proteins to bud transport vesicles}, author={Frantisek Supek and David T. Madden and Susan T. Hamamoto and Lelio Orci and Randy Schekman}, journal={The Journal of Cell Biology}, year={2002}, volume={158}, pages={1029 - 1038} }