Corpus ID: 27799432

Sec 72 p Contributes to the Selective Recognition of Signal Peptides by the Secretory l lypeptide Transl ation Complex

@inproceedings{Feldheim2002Sec7P,
  title={Sec 72 p Contributes to the Selective Recognition of Signal Peptides by the Secretory l lypeptide Transl ation Complex},
  author={D. Feldheim and y Schekman},
  year={2002}
}

D. Feldheim, y Schekman

Published 2002

SEC72 encodes the 23-kD subunit of the Sec63p complex, an integral ER membrane protein complex that is required for translocation of presecretory proteins into the ER of Saccharomyces cerevisiae. DNA sequence analysis of SEC72 predicts a 21.6-kD protein with neither a signal peptide nor any transmembrane domains. Antibodies directed against a carboxyl-terminal peptide of Sec72p were used to confirm the membrane location of the protein. SEC72 is not essential for yeast cell growth, although an… CONTINUE READING

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