Seasonality of antibiotic-resistant streptococcus pneumoniae that causes acute otitis media: a clue for an antibiotic-restriction policy?

@article{Dagan2008SeasonalityOA,
  title={Seasonality of antibiotic-resistant streptococcus pneumoniae that causes acute otitis media: a clue for an antibiotic-restriction policy?},
  author={Ron Dagan and Galia Barkai and Noga Givon-Lavi and Amir Z Sharf and Daniel A. Vardy and Ted Cohen and Marc Lipsitch and David Greenberg},
  journal={The Journal of infectious diseases},
  year={2008},
  volume={197 8},
  pages={
          1094-102
        }
}
BACKGROUND It is unclear whether reducing antibiotic prescriptions can reduce rates of resistance once resistance becomes prevalent. We attempted to determine whether reduced antibiotic consumption, which is observed yearly in children during the warm season, is associated with a reduction in antibiotic resistance in pneumococcal acute otitis media (AOM). METHODS Antibiotic prescriptions and resistance were measured prospectively during 1999-2003 in 2 demographically distinct populations… CONTINUE READING
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