Seasonal variations of interleukin-4 and interferon-gamma release by peripheral blood mononuclear cells from atopic subjects stimulated by polyclonal activators.

@article{Lagier1995SeasonalVO,
  title={Seasonal variations of interleukin-4 and interferon-gamma release by peripheral blood mononuclear cells from atopic subjects stimulated by polyclonal activators.},
  author={B. Lagier and N. Pons and A. Rivier and I. Chanal and P. Chanez and J. Bousquet and J. P{\`e}ne},
  journal={The Journal of allergy and clinical immunology},
  year={1995},
  volume={96 6 Pt 1},
  pages={
          932-40
        }
}
  • B. Lagier, N. Pons, +4 authors J. Pène
  • Published 1995
  • Biology, Medicine
  • The Journal of allergy and clinical immunology
  • IgE synthesis is controlled by interleukin (IL)-4 and interferon (IFN)-gamma, but there is heterogeneity in the IL-4 response depending on the sensitization of patients and natural allergen exposure. In patients sensitized to various allergens, we studied the synthesis of IL-4, IFN-gamma, and IgE to determine to what extent their in vitro immune response may be influenced by pollen season, depending on their sensitization. We studied 12 nonallergic individuals, seven patients sensitized to… CONTINUE READING
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