Seasonal changes in the suprachiasmatic nucleus of man

  title={Seasonal changes in the suprachiasmatic nucleus of man},
  author={Michel A. Hofman and Dick F. Swaab},
  journal={Neuroscience Letters},

Diurnal and Seasonal Rhythms of Neuronal Activity in the Suprachiasmatic Nucleus of Humans

Investigation of the brains of 30 young human subjects found that the daily light-dark cycle as well as seasonal variations in photoperiod would affect the vasopressin cell population of the human SCN.

The suprachiasmatic nuclei as a seasonal clock

The human suprachiasmatic nucleus (SCN) in a periodic environment

The human suprachiasmatic nucleus (SCN) is a small structure situated on top of the optic chiasm that shows up clearly following staining of its peptidergic neurotransmitters, e.

Functional neuroanatomy and neuropathology of the human hypothalamus

The human hypothalamus is involved in a wide range of functions in the developing, adult and aging subject and is responsible for a large number of symptoms of neuroendocrine, neurological and

Development of the human hypothalamus

  • D. Swaab
  • Biology
    Neurochemical Research
  • 2005
It can be concluded that the various hypothalamic nuclei are involved in a great number of functions and show clear and differential changes in development with respect to sexual differentiation, birth and a number of diseases.



Morphometric analysis of the suprachiasmatic and paraventricular nuclei in the human brain: sex differences and age-dependent changes.

A comparison of the volumetric measurements of the human SCN and PVN with those of the rat showed that the humanSCN is reduced in size relative to other hypothalamic nuclei, mainly caused by cell loss rather than by a reduction in cell size.

Circadian neural rhythms in mammals.

  • F. Turek
  • Biology, Psychology
    Annual review of physiology
  • 1985
There is no conclusive evidence that circadian rhythms can be generated over a prolonged period of time in the absence of the SCN in mammals maintained under constant environmental conditions, and recent studies in humans suggest that disorders within the circadian system itself may be involved in the etiology of at least some forms of mental illness.

Putative melatonin receptors in a human biological clock.

The results suggest that putative melatonin receptors are located in a human biological clock, and specifically found in the suprachiasmatic nuclei of hypothalami from adults and fetuses.