Seasonal Affective Disorder and Serotonin-Related Polymorphisms

  title={Seasonal Affective Disorder and Serotonin-Related Polymorphisms},
  author={C. Johansson and C. Smedh and T. Partonen and P. Pekkarinen and M. Schalling},
  journal={Neurobiology of Disease},
  • C. Johansson, C. Smedh, +2 authors M. Schalling
  • Published 2001
  • Biology, Medicine
  • Neurobiology of Disease
  • Disturbances in central serotonergic systems have been hypothesized to be involved in seasonal affective disorder (SAD). Association between SAD and the shorter allele of the serotonin transporter promoter repeat length polymorphism (5-HTTLPR) has been reported in an American sample. We have genotyped 82 SAD patients and 82 healthy controls from Sweden, Finland, and Germany for this and five other polymorphisms in the genes coding for serotonin receptors 5-HT2A and 5-HT2C, tryptophan… CONTINUE READING
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