Seasonal Affective Disorder

@article{Partonen1991SeasonalAD,
  title={Seasonal Affective Disorder},
  author={Timo Partonen and Jouko L{\"o}nnqvist},
  journal={CNS Drugs},
  year={1991},
  volume={9},
  pages={203-212}
}
SummarySeasonal affective disorder (SAD) is characterised by recurrent depressive episodes, occurring typically in winter (i.e. winter SAD). The atypical symptoms of depression frequently precede the onset of each episode and are closely associated with the recurrence of the episodes. Winter depressive episodes are mostly of mild to moderate severity. Patients with winter SAD seldom require hospitalisation, have psychotic symptoms or are at risk of suicide. However, most patients do experience… Expand
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References

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AbstractSeasonal affective disorder (SAD) is a subtype of recurrent mood disorders distinguished by recurring major depressions during the winter months and symptom remission during the summer. AExpand
Pharmacological responsiveness of winter depression.
TLDR
Seasonal affective disorders (SADs) are disturbances of mood bearing a fixed relationship to season, and Chronobiologic properties that might explain or predict the effectiveness of drugs used to treat winter depression are discussed. Expand
Seasonal affective disorder: rapid resolution by low-dose alprazolam.
TLDR
Alprazolam may represent an effective and well-tolerated alternative treatment for SAD and produced rapid and dramatic results in 4 patients, with remission of symptoms occurring in about 3 days. Expand
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TLDR
The results emphasize that DSM-III-R seasonal mood disorder includes severe cases of recurrent depression and bipolar disorder and support a distinction between two seasonal subtypes. Expand
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TLDR
Preliminary studies in 11 patients suggest that extending the photoperiod with bright artificial light has an antidepressant effect and sleep recordings in nine depressed patients confirmed the presence of hypersomnia and showed increased sleep latency and reduced slow-wave (delta) sleep. Expand
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TLDR
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TLDR
The results of this open trial suggest that bupropion is an effective treatment for winter depression, however, controlled studies are required to confidently determine whether this is the case. Expand
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TLDR
Predictor analysis showed a remarkably high negative correlation between improvement at 3 weeks (extended MADRS) and age in the placebo group and a strong, nonsignificant trend in the same direction in the moclobemide group. Expand
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TLDR
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TLDR
In the first study assessing responsiveness of winter depression to a standard pharmacologic treatment for depression, the authors found that 14 patients meeting National Institute of Mental Health criteria for winter depression responded to treatment with tranylcypromine. Expand
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