Searching for “the Top” in Top-Down Control

  title={Searching for “the Top” in Top-Down Control},
  author={Brian T. Miller and M. D'Esposito},
  • Brian T. Miller, M. D'Esposito
  • Published 2005
  • Psychology, Medicine
  • Neuron
  • Although numerous theoretical models implicate the prefrontal cortex (PFC) as a source of top-down control signals, empirical support is limited. In this review, we highlight direct evidence for this view of PFC function and discuss several lines of other supportive findings. Most evidence to-date is only suggestive due to methodological challenges in tracking the spatiotemporal dynamics of cortical networks. However, we discuss several promising approaches that could further our understanding… CONTINUE READING
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