Search for the tumor-related proteins of transition cell carcinoma in Taiwan by proteomic analysis.

@article{Sheng2006SearchFT,
  title={Search for the tumor-related proteins of transition cell carcinoma in Taiwan by proteomic analysis.},
  author={Kun-Hung Sheng and Yu-Xia Yao and Shih-sung Chuang and Hung Shan Wu and Ting Yao Wu},
  journal={Proteomics},
  year={2006},
  volume={6 3},
  pages={
          1058-65
        }
}
To better understand the carcinogenesis of bladder cancer in Taiwan, we utilized the proteomic approach to search for potential biomarkers of transitional cell carcinoma (TCC). Analysis by 2-DE and MS/MS indicated that seven proteins are down-regulated and three proteins up-regulated in grade III samples as compared with those of grade II. Of these deregulated proteins, fatty acid binding proteins, annexin V, heat-shock protein 27, and lactate dehydrogenase have been shown to be associated with… CONTINUE READING
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