Search for the missing lncs: gene regulatory networks in neural crest development and long non‐coding RNA biomarkers of Hirschsprung's disease

@article{Rogers2016SearchFT,
  title={Search for the missing lncs: gene regulatory networks in neural crest development and long non‐coding RNA biomarkers of Hirschsprung's disease},
  author={J. M. Rogers},
  journal={Neurogastroenterology \& Motility},
  year={2016},
  volume={28}
}
  • J. M. Rogers
  • Published 2016
  • Medicine
  • Neurogastroenterology & Motility
Hirschsprung's disease (HSCR), a birth defect characterized by variable aganglionosis of the gut, affects about 1 in 5000 births and is a consequence of abnormal development of neural crest cells, from which enteric ganglia derive. In the companion article in this issue (Shen et al., Neurogasterenterol Motil 28: 266–73), the authors search for long non‐coding RNAs (lncRNAs) differentially expressed in bowel tissues of infants with HSCR. Microarray analysis of over 37 000 lncRNAs and 34 000… Expand
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