Search for rearrangements and/or allelic loss of the fas/APO-1 gene in 101 human lymphomas.

@article{Xerri1995SearchFR,
  title={Search for rearrangements and/or allelic loss of the fas/APO-1 gene in 101 human lymphomas.},
  author={Luc Xerri and Nadine Carbuccia and Prof. R. Parc and Françoise Birg},
  journal={American journal of clinical pathology},
  year={1995},
  volume={104 4},
  pages={424-30}
}
The authors analyzed the possible occurrence of rearrangements and/or allelic loss of the fas/APO-1 gene in a representative series of human lymphomas, including 101 cases of Hodgkin's disease (HD) and non-Hodgkin's lymphomas (NHL). The rationale for this study was double. Chromosome 10 alterations, frequently observed in lymphoma subtypes, encompass the chromosomal localization of fas/APO-1. In addition, Ipr mouse mutants, which present with a generalized lymphoproliferative disease, were… CONTINUE READING

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