Search for novel redox groups in mitochondrial NADH:ubiquinone oxidoreductase (complex I) by diode array UV/VIS spectroscopy.

@article{Schulte1998SearchFN,
  title={Search for novel redox groups in mitochondrial NADH:ubiquinone oxidoreductase (complex I) by diode array UV/VIS spectroscopy.},
  author={Ulrich Schulte and Andrea Abelmann and N Amling and Benedikt Brors and Thorsten Friedrich and L Kintscher and T. S. Rasmussen and Hanns Weiss},
  journal={BioFactors},
  year={1998},
  volume={8 3-4},
  pages={177-86}
}
The proton-translocating NADH:ubiquinone oxidoreductase of mitochondria (complex I) is a large L-shaped multisubunit complex. The peripheral matrix arm contains one FMN and a number of iron-sulfur (FeS) clusters and is involved in NADH oxidation and electron transfer to the membrane intrinsic arm. There, following a yet unknown mechanism, the redox-driven proton translocation and the ubiquinone reduction take place. Redox groups that would be able to link electron transfer with proton… CONTINUE READING