Search for noncompetitive 2-amino-3- (3-hydroxy-5-methyl-4-isoxazolyl)propionic acid receptor (AMPAR) antagonists: Synthesis, pharmacological properties, and computational studies*

Abstract

The development of new 2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor (AMPAR) negative modulators has received considerable interest due to their crucial role in specific neurological diseases. In recent years, our research group has been engaged in the development of new AMPAR ligands and chemical and biological studies of… (More)

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Cite this paper

@inproceedings{Chimirri2004SearchFN, title={Search for noncompetitive 2-amino-3- (3-hydroxy-5-methyl-4-isoxazolyl)propionic acid receptor (AMPAR) antagonists: Synthesis, pharmacological properties, and computational studies*}, author={Alexander Chimirri and Giuliano Sarro and Susan Elisabeth Quartarone and Maria Letizia Barreca and Rafael Caruso and L. De Luca and Rosaria Gitto}, year={2004} }