Search for correlations between genotypes and electrophysiological patterns in migraine: the MTHFR C677T polymorphism and visual evoked potentials.

@article{Magis2007SearchFC,
  title={Search for correlations between genotypes and electrophysiological patterns in migraine: the MTHFR C677T polymorphism and visual evoked potentials.},
  author={Delphine Magis and Marta Allena and Gianluca Coppola and Laura Di Clemente and Pascale G{\'e}rard and Jean Schoenen},
  journal={Cephalalgia : an international journal of headache},
  year={2007},
  volume={27 10},
  pages={1142-9}
}
Interictally, migraineurs have on average a reduction in habituation of pattern-reversal visual evoked potentials (PR-VEP) and in mitochondrial energy reserve. 5,10-Methylenetetrahydrofolate reductase (MTHFR) is involved in folate metabolism and its C677T polymorphism may be more prevalent in migraine. The aim of this study was to search in migraineurs for a correlation between the MTHFR C677T polymorphism and the PR-VEP profile. PR-VEP were recorded in 52 genotyped migraine patients: 40 female… CONTINUE READING