Search for Putative Virulence Factors of Helicobacter pylori (The Low-Molecular-Weight (33-35 K) Antigen)

  title={Search for Putative Virulence Factors of Helicobacter pylori (The Low-Molecular-Weight (33-35 K) Antigen)},
  author={Yoshio Yamaoka and Tadashi Kodama and David Y Graham and Kei Kashima},
  journal={Digestive Diseases and Sciences},
Early studies suggested that two Helicobacterpylori proteins, CagA and VacA, were virulence factors.Support for that hypothesis has been undermined bygeographic differences in prevalence of these antigens. To identify other possible putative virulencefactors by establishing a relationship between antigensand different H. pylori diseases, two commercialavailable immunoblot assay kits, HelicoBlot 2.0(Genelabs Diagnostics, Singapore) and RIDA BlotHelicobacter (R-Biopharm GmbH, Darmstadt, Germany… CONTINUE READING
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