Search for Alzheimer's disease biomarkers in blood cells: hypotheses-driven approach.

@article{Wojsiat2017SearchFA,
  title={Search for Alzheimer's disease biomarkers in blood cells: hypotheses-driven approach.},
  author={Joanna Wojsiat and Katarzyna Laskowska-Kaszub and Anna Mietelska-Porowska and Urszula Wojda},
  journal={Biomarkers in medicine},
  year={2017},
  volume={11 10},
  pages={
          917-931
        }
}
Current Alzheimer's disease (AD) diagnostics is based on cognitive testing, and detecting amyloid Aβ and τ pathology by brain imaging and assays of cerebrospinal fluid. However, biomarkers identifying complex pathways contributing to pathology are lacking, especially for early AD. Preferably, such biomarkers should be more cost-effective and present in easily available diagnostic tissues, such as blood. Here, we summarize the recent findings of potential early AD molecular diagnostic biomarkers… CONTINUE READING
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