Search engine processor: Filtering and organizing peptide spectrum matches.

  title={Search engine processor: Filtering and organizing peptide spectrum matches.},
  author={Paulo Costa Carvalho and Juliana S. G. Fischer and Tao Xu and Daniel Cociorva and Tiago Santana Balbuena and Richard Hemmi Valente and Jonas Perales and John R. Yates and Valmir C. Barbosa},
  volume={12 7},
The search engine processor (SEPro) is a tool for filtering, organizing, sharing, and displaying peptide spectrum matches. It employs a novel three-tier Bayesian approach that uses layers of spectrum, peptide, and protein logic to lead the data to converge to a single list of reliable protein identifications. SEPro is integrated into the PatternLab for proteomics environment, where an arsenal of tools for analyzing shotgun proteomic data is provided. By using the semi-labeled decoy approach for… CONTINUE READING
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