Sea urchin development: an alternative model for mechanistic understanding of neurodevelopment and neurotoxicity.

@article{Falugi2008SeaUD,
  title={Sea urchin development: an alternative model for mechanistic understanding of neurodevelopment and neurotoxicity.},
  author={Carla Falugi and Maria Lammerding-Koppel and Maria Grazia Aluigi},
  journal={Birth defects research. Part C, Embryo today : reviews},
  year={2008},
  volume={84 3},
  pages={
          188-203
        }
}
Echinoderm early developmental stages might supply a good tool for toxicity testing in different fields, ranging from environment to food contamination, and in full respect of the 3Rs objectives (reduction, refinement, and replacement of animal experiments) that will eventually lead to the replacement of high vertebrate animal testing in toxicology. Sea urchin is one of the few organismic models considered by the European Agency for Alternative models. Actually, sea urchin embryonic development… CONTINUE READING