Sculpting the endomembrane system in deep time: high resolution phylogenetics of Rab GTPases.

@article{Eli2012SculptingTE,
  title={Sculpting the endomembrane system in deep time: high resolution phylogenetics of Rab GTPases.},
  author={Marek Eli{\'a}{\vs} and Andrew Brighouse and Carme Gabernet-Castello and Mark C. Field and Joel B Dacks},
  journal={Journal of cell science},
  year={2012},
  volume={125 Pt 10},
  pages={2500-8}
}
The presence of a nucleus and other membrane-bounded intracellular compartments is the defining feature of eukaryotic cells. Endosymbiosis accounts for the origins of mitochondria and plastids, but the evolutionary ancestry of the remaining cellular compartments is incompletely documented. Resolving the evolutionary history of organelle-identity encoding proteins within the endomembrane system is a necessity for unravelling the origins and diversification of the endogenously derived organelles… CONTINUE READING
Highly Influential
This paper has highly influenced 10 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 57 extracted citations

Are There Rab GTPases in Archaea?

Molecular biology and evolution • 2016
View 7 Excerpts
Highly Influenced

Rab18 and a Rab18 GEF complex are required for normal ER structure

The Journal of cell biology • 2014
View 4 Excerpts
Highly Influenced

Expanding proteostasis by membrane trafficking networks.

Cold Spring Harbor perspectives in medicine • 2013
View 4 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 55 references

Rab GTPases as coordinators of vesicle traffic

Nature Reviews Molecular Cell Biology • 2009
View 19 Excerpts
Highly Influenced

The Arabidopsis Rab GTPase family: another enigma variation.

Current opinion in plant biology • 2002
View 5 Excerpts
Highly Influenced

Evolution of the Rab family of small GTP-binding proteins.

Journal of molecular biology • 2001
View 8 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…