Sculpting the endomembrane system in deep time: high resolution phylogenetics of Rab GTPases.

  title={Sculpting the endomembrane system in deep time: high resolution phylogenetics of Rab GTPases.},
  author={Marek Eli{\'a}{\vs} and Andrew Brighouse and Carme Gabernet-Castello and Mark C. Field and Joel B Dacks},
  journal={Journal of cell science},
  volume={125 Pt 10},
The presence of a nucleus and other membrane-bounded intracellular compartments is the defining feature of eukaryotic cells. Endosymbiosis accounts for the origins of mitochondria and plastids, but the evolutionary ancestry of the remaining cellular compartments is incompletely documented. Resolving the evolutionary history of organelle-identity encoding proteins within the endomembrane system is a necessity for unravelling the origins and diversification of the endogenously derived organelles… CONTINUE READING
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