Scube2 mediates Hedgehog signalling in the zebrafish embryo.

@article{Hollway2006Scube2MH,
  title={Scube2 mediates Hedgehog signalling in the zebrafish embryo.},
  author={Georgina E Hollway and John Maule and Philippe Gautier and Timothy M. Evans and David G Keenan and Claudia Lohs and Danielle Fischer and Carol Wicking and Peter David Currie},
  journal={Developmental biology},
  year={2006},
  volume={294 1},
  pages={
          104-18
        }
}
  • Georgina E Hollway, John Maule, +6 authors Peter David Currie
  • Published in Developmental biology 2006
  • Biology, Medicine
  • The Hedgehog family of secreted morphogens specifies the fate of a large number of different cell types within invertebrate and vertebrate embryos, including the muscle cell precursors of the embryonic myotome of zebrafish. Formation of Hedgehog-sensitive muscle fates is disrupted within homozygous zebrafish mutants of the "you"-type class, the majority of which disrupt components of the Hedgehog (HH) signal transduction pathway. We have undertaken a phenotypic and molecular characterisation of… CONTINUE READING

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