Screening the cytotoxicity of single-walled carbon nanotubes using novel 3D tissue-mimetic models.

@article{Movia2011ScreeningTC,
  title={Screening the cytotoxicity of single-walled carbon nanotubes using novel 3D tissue-mimetic models.},
  author={Dania Movia and Adriele Prina-Mello and Despina Bazou and Yuri Volkov and Silvia Giordani},
  journal={ACS nano},
  year={2011},
  volume={5 11},
  pages={9278-90}
}
Single-walled carbon nanotubes (SWNTs) are promising candidates for a wide range of biomedical applications due to their fascinating properties. However, safety concerns are raised on their potential human toxicity and on the techniques that need to be used to assess such toxicity. Here, we integrate for the first time 3D tissue-mimetic models in the cytotoxicity assessment of purified (p-) and oxidized (o-) SWNTs. An established ultrasound standing wave trap was used to generate the 3D cell… CONTINUE READING
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