Screening strategies for discovery of antibacterial natural products.

@article{Singh2011ScreeningSF,
  title={Screening strategies for discovery of antibacterial natural products.},
  author={S Bhaskar Singh and Katherine W. Young and Lynn Miesel},
  journal={Expert review of anti-infective therapy},
  year={2011},
  volume={9 8},
  pages={589-613}
}
Microbial-derived natural products have been a traditional source of antibiotics and antibiotic leads and continue to be effective sources of antibiotics today. The most important of these discoveries were made about 50 years ago. Chemical modifications of natural products discovered during those years continue to produce new clinical agents but their value is now, unfortunately, fading away owing to the exhaustion of opportunities of chemical modifications. The discovery of new natural… CONTINUE READING

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