Screening panels for detection of monoclonal gammopathies.

@article{Katzmann2009ScreeningPF,
  title={Screening panels for detection of monoclonal gammopathies.},
  author={Jerry A. Katzmann and Robert A Kyle and J. W. Benson and Dirk Russell Larson and Melissa R. Snyder and John A. Lust and S Vincent Rajkumar and Angela Dispenzieri},
  journal={Clinical chemistry},
  year={2009},
  volume={55 8},
  pages={1517-22}
}
BACKGROUND The repertoire of serologic tests for identifying a monoclonal gammopathy includes serum and urine protein electrophoresis (PEL), serum and urine immunofixation electrophoresis (IFE), and quantitative serum free light chain (FLC). Although there are several reports on the relative diagnostic contribution of these assays, none has looked at the tests singly and in combination for the various plasma cell proliferative disorders (PCPDs). METHODS Patients with a PCPD and all 5 assays… CONTINUE READING

3 Figures & Tables

Connections & Topics

Mentioned Connections BETA
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
n = 191 ) , monoclonal gammopathy of undetermined significance ( MGUS ) ( n = 524 ) , plasmacytoma ( n = 29 ) , extramedullary plasmacytoma ( n = 10 ) , Waldenström macroglobulinemia ( WM ) ( n = 26 ) , primary amyloidosis ( AL ) ( n = 581 ) , light chain deposition disease ( LCDD ) ( n = 18 ) , and POEMS syndrome ( n = 31 ) .
The diagnoses were multiple myeloma ( MM ) ( n = 467 ) , smoldering multiple myeloma ( SMM ) (
All Topics