Screening of phthalate esters in 47 branded perfumes

  title={Screening of phthalate esters in 47 branded perfumes},
  author={Iman Al-Saleh and Rola Elkhatib},
  journal={Environmental Science and Pollution Research},
In the last few years, the use of phthalates in perfumes has gained attention because these chemicals are sometimes added intentionally as a solvent and a fixative. Five phthalate esters, dimethyl phthalate (DMP), diethyl phthalate (DEP), dibutyl phthalate (DBP), benzyl butyl phthalate (BBP), and diethyl hexyl phthalate (DEHP), were measured in 47 branded perfumes using headspace solid phase microextraction (SPME) followed by gas chromatography–mass spectrometry (GC-MS). The results revealed… 

Evaluating the potential genotoxicity of phthalates esters (PAEs) in perfumes using in vitro assays

This study demonstrates for the first time the possible contribution of PAEs in perfumes to DNA damage and suggests that their use as solvents or fixatives should be regulated.

Occurrence and distribution of phthalates in sanitary napkins from six countries: implications for women's health.

The calculated health risks of phthalates in sanitary napkins were generally low, but the carcinogenic risks in some samples exceeded acceptable levels, and more research is required to investigate the contaminations in sanitarian napkins and associated with risks to women.

Determination of total phthalate in cosmetics using a simple three-phase sample preparation method

The validated method was applied for the analysis of 57 commercial cosmetic samples and found no obvious matrix effect existed in the different cosmetics matrices.

The extent and predictors of phthalate exposure among couples undergoing in vitro fertilization treatment

Several potential predictors for the variations in specific urinary phthalate metabolites were identified, including the body mass index, age, socioeconomic status, and regional distribution for both women and their male partners but with slightly different patterns.

Development and validation of a dispersive liquid–liquid microextraction method for the determination of phthalate esters in perfumes using gas chromatography-mass spectrometry

A simple, rapid, sensitive and eco-friendly method has been developed for the simultaneous determination, preconcentration and extraction of phthalate esters (dimethyl phthalate, diethyl phthalate,



A survey of phthalate esters in consumer cosmetic products.

Thirty-one of the 60 adult-use and baby-care cosmetic products were found to contain at least one phthalate ester and spiked recoveries in antiperspirant and nail color ranged from 88% to 104%.


  • H. KooB. Lee
  • Medicine
    Journal of toxicology and environmental health. Part A
  • 2004
The data suggest that estimated exposure to phthalates in the cosmetics mentioned are relatively small, however, total exposure levels from several sources may be greater and require further investigation.

Analysis of consumer cosmetic products for phthalate esters.

The FDA has concluded that there is insufficient data to conclude that a human health hazard exists from exposure to phthalate esters from cosmetic products.

A survey of phthalates and parabens in personal care products from the United States and its implications for human exposure.

PCPs are an important source of human exposure to parabens; the contribution of PCPs to phthalate exposure is low, except for DEP.

Simultaneous determination of seven phthalates and four parabens in cosmetic products using HPLC-DAD and GC-MS methods.

The predominant phthalates and parabens detected in the studied samples were methylparaben, propylparABen, diethyl phthalate, dibutyl phTHC, dicyclohexylphthalates, and di-(2-ethylhexyl)phthalate.

Dermal absorption of phthalate diesters in rats.

Effect of phthalate esters on reproduction in rats.

The present study was undertaken to determine the effects of dibutyl phthalate, dimethyl phthalates, and di-2-ethylhexylphthalate on embryonic development and parturition.

Chemical behavior of phthalates under abiotic conditions in landfills.

It is asserted that hydrolysis of phthalate esters in lower landfill layers is the dominant process for transforming these esters; in contrast, biodegradation is the predominant process in the upper landfill layers.

Developmental toxicity evaluation of diethyl and dimethyl phthalate in rats.

There was no effect of DEP or DMP treatment on any parameter of embryo/fetal development, except an increased incidence of supernumerary ribs (a variation) in the 5% DEP group, and these results do not support the conclusion of other investigators that DEP and DMP are potent developmental toxicants.