Screening of medicinal plants used in South African traditional medicine for genotoxic effects.

@article{Elgorashi2003ScreeningOM,
  title={Screening of medicinal plants used in South African traditional medicine for genotoxic effects.},
  author={Esameldin E Elgorashi and Joslyn L S Taylor and Annemarie Maes and Johannes van Staden and Norbert De Kimpe and Luc Verschaeve},
  journal={Toxicology letters},
  year={2003},
  volume={143 2},
  pages={195-207}
}
Dichloromethane and 90% methanol extracts from 51 South African medicinal plants were evaluated for potential genotoxic effects using the bacterial Ames and VITOTOX tests with and without metabolic activation. Dichloromethane extracts from bulbs of Crinum macowanii showed mutagenicity in strain TA98 with and without metabolic activation, whereas extracts from leaves of Chaetacme aristata and foliage of Plumbago auriculata showed mutagenicity and/or toxicity. Extracts from the leaves of… CONTINUE READING

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