Screening of human LPHN3 for variants with a potential impact on ADHD susceptibility.

  title={Screening of human LPHN3 for variants with a potential impact on ADHD susceptibility.},
  author={Sabina Domen{\'e} and Horia Stanescu and Deeann Wallis and Bradford Tinloy and Daniel E Pineda and Robert Kleta and Mauricio Arcos-Burgos and Erich Roessler and Maximilian Muenke},
  journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics},
  volume={156B 1},
Attention deficit hyperactivity disorder (ADHD) is the most common behavioral disorder in childhood, and often has effects detectable into adulthood. Advances in genetic linkage and association analysis have begun to elucidate some of the genetic factors underlying this complex disorder. Recently, we identified LPHN3, a novel ADHD susceptibility gene harbored in 4q, and showed that a LPHN3 common haplotype confers susceptibility to ADHD and predicts effectiveness of stimulant medication. Here… CONTINUE READING
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