Screening of genes encoding junctional candidates in arrhythmogenic right ventricular cardiomyopathy/dysplasia.

@article{Gandjbakhch2013ScreeningOG,
  title={Screening of genes encoding junctional candidates in arrhythmogenic right ventricular cardiomyopathy/dysplasia.},
  author={Estelle Gandjbakhch and Alexia Vite and Françoise Gary and V{\'e}ronique Fressart and Erwan Donal and Françoise Simon and Françoise Hidden-Lucet and Michel Komajda and Philippe Charron and Eric Villard},
  journal={Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology},
  year={2013},
  volume={15 10},
  pages={1522-5}
}
AIMS Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is an inherited cardiomyopathy characterized by fibro-fatty replacement of the right ventricle and ventricular arrhythmias. The major disease-causing genes encode cardiac desmosomal components but are involved in only ∼50% of patients. To identify the missing genetic determinants, we used a candidate gene approach, focusing on the 3'-untranslated region (UTR) of the main ARVC/D gene PKP2 and on additional genes involved in… CONTINUE READING