Screening of gap junction antagonists on dye coupling in the rabbit retina.

@article{Pan2007ScreeningOG,
  title={Screening of gap junction antagonists on dye coupling in the rabbit retina.},
  author={Feng Pan and Stephen L. Mills and Stephen C. Massey},
  journal={Visual neuroscience},
  year={2007},
  volume={24 4},
  pages={609-18}
}
Many cell types in the retina are coupled via gap junctions and so there is a pressing need for a potent and reversible gap junction antagonist. We screened a series of potential gap junction antagonists by evaluating their effects on dye coupling in the network of A-type horizontal cells. We evaluated the following compounds: meclofenamic acid (MFA), mefloquine, 2-aminoethyldiphenyl borate (2-APB), 18-alpha-glycyrrhetinic acid, 18-beta-glycyrrhetinic acid (18-beta-GA), retinoic acid… CONTINUE READING
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