Screening of anti-human leukocyte monoclonal antibodies for reactivity with equine leukocytes.

@article{Ibrahim2007ScreeningOA,
  title={Screening of anti-human leukocyte monoclonal antibodies for reactivity with equine leukocytes.},
  author={Sherif Y Ibrahim and Kelly Saunders and Julia H Kydd and David P. Lunn and Falko Steinbach},
  journal={Veterinary immunology and immunopathology},
  year={2007},
  volume={119 1-2},
  pages={63-80}
}
Three hundred and seventy-nine monoclonal antibodies (mAbs) against various human CD molecules supplied to the HLDA8 animal homologues section (including four isotype controls) were analysed for cross-reactivity with equine leukocytes. First, flow cytometric identification of positively reacting mAbs was performed in one laboratory. Thereafter, a second round of flow cytometric evaluation was performed, involving three laboratories participating in the study. The first test-round indicated 17… CONTINUE READING