Screening of Neisseria gonorrhoeae for tolerant response to beta-lactam antibiotics.

@article{Repentigny1981ScreeningON,
  title={Screening of Neisseria gonorrhoeae for tolerant response to beta-lactam antibiotics.},
  author={Louis de Repentigny and Patrice Turgeon},
  journal={Antimicrobial agents and chemotherapy},
  year={1981},
  volume={19 4},
  pages={
          645-8
        }
}
Minimal inhibitory concentrations (MICs) and minimal bactericidal concentrations (MBCs) of penicillin, ampicillin, cefoxitin, and cefuroxime were determined for 103 beta-lactamase-negative Neisseria gonorrhoeae clinical isolates belonging to five different auxotypes. MBC determinations were base on killing 99.9% of the inoculum after 24 h of incubation. The MBC/MIC ratio was less than or equal to 8 for ampicillin, cefoxitin, and cefuroxime in all 103 strains. Two isolates which were very… CONTINUE READING
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