Screening isolates from antibody phage-display libraries.

Abstract

Antibody phage display, coupled with automated screening, facilitates and potentiates the mining of complex combinatorial libraries and the identification of potent drug leads. In managing phage screening data, the behavior of individual phage isolates in binding assays must be linked to their antibody identities as deduced from DNA sequencing. Reviewed… (More)
DOI: 10.1016/j.drudis.2007.10.012

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