Screening for tyrosinase inhibitors among extracts of seashore plants and identification of potent inhibitors from Garcinia subelliptica.

@article{Masuda2005ScreeningFT,
  title={Screening for tyrosinase inhibitors among extracts of seashore plants and identification of potent inhibitors from Garcinia subelliptica.},
  author={Toshiya Masuda and Daiki Yamashita and Yoshio Takeda and Shigetomo Yonemori},
  journal={Bioscience, biotechnology, and biochemistry},
  year={2005},
  volume={69 1},
  pages={197-201}
}
The tyrosinase inhibitory activity of methanol extracts of the leaves of 39 plant species growing on the seashore of Iriomote island (Okinawa, Japan) was investigated. The extracts of Hibiscus tiliaceus, Carex pumila, and Garcinia subelliptica showed potent activity among them. The inhibitors in the extract of Garcinia subelliptica were purified by assay-guided fractionation to give two biflavonoids. These were known compounds (2R,3S-5,7,4',5'',7'',3''',4'''-heptahydroxy flavanone[3-8… CONTINUE READING