Screening for trisomy 21 in twins using first trimester ultrasound and maternal serum biochemistry in a one-stop clinic: a review of three years experience.

@article{Spencer2003ScreeningFT,
  title={Screening for trisomy 21 in twins using first trimester ultrasound and maternal serum biochemistry in a one-stop clinic: a review of three years experience.},
  author={Kevin Spencer and Kypros H. Nicolaides},
  journal={BJOG : an international journal of obstetrics and gynaecology},
  year={2003},
  volume={110 3},
  pages={
          276-80
        }
}
OBJECTIVE To evaluate the performance of screening for fetal trisomy 21 in the first trimester of twin pregnancies by a combination of maternal serum biochemistry and ultrasonography. DESIGN Three year retrospective review of screening performance. SETTING District General Hospital maternity unit. POPULATION All women booked to receive routine antenatal care at Harold Wood Hospital between 1 June 1998 and 30th September 2001. The population included 13,940 women of all ages presenting… CONTINUE READING

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