Screening for the Location of RNA using the Chloride Ion Distribution in Simulations of Virus Capsids.

Abstract

The complete structure of the genomic material inside a virus capsid remains elusive, although a limited amount of symmetric nucleic acid can be resolved in the crystal structure of 17 icosahedral viruses. The negatively charged sugar-phosphate backbone of RNA and DNA as well as the large positive charge of the interior surface of the virus capsids suggest… (More)
DOI: 10.1021/ct3002128

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