Screening for novel plant sources of prenyloxyanthraquinones: Senna alexandrina Mill. and Aloe vera (L.) Burm. F.

@article{Epifano2015ScreeningFN,
  title={Screening for novel plant sources of prenyloxyanthraquinones: Senna alexandrina Mill. and Aloe vera (L.) Burm. F.},
  author={Francesco Epifano and Serena Fiorito and Marcello Locatelli and Vito Alessandro Taddeo and Salvatore Genovese},
  journal={Natural Product Research},
  year={2015},
  volume={29},
  pages={180 - 184}
}
As a continuation of our ongoing studies aimed to reveal the presence of oxyprenylated anthraquinones in plants claimed to have a laxative effect, in this article, we describe the extraction and HPLC separation of madagascin (3-isopentenyloxyemodin) and 3-geranyloxyemodine from dried leaves and fruits of Senna alexandrina Mill. (Leguminosae) and leaves and gel of Aloe vera (L.) Burm. F. (Xanthorrhoeaceae). Both compounds are described herein for the first time as components of extracts of the… 
The genus Senna (Fabaceae): A review on its traditional uses, botany, phytochemistry, pharmacology and toxicology
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Chemical Constituents, Antimicrobial Activity, and Food Preservative Characteristics of Aloe vera Gel
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Three new anthraquinone glycosides, alaternosides A-C, were isolated and elucidated together with the two known anthraquone glyCosides, Physcion-8-O-rutinoside and emodin-6- o-α-L-rhamnoside as well as with the known kaempferol-7-methylether and β-sitosterol.
Recent update on the medicinal properties and use of Aloe vera in the treatment of various ailments
Aloe vera (Aloe barbadensis) an herb is widely used in Ayurvedic, Homoeopathic and Allopathic streams for its marvelous medicinal properties. This plant is one of the richest natural sources of
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The potentialities as skin tanning or whitening agents of a wider panel of natural and semisynthetic aromatic compounds, including coumarins, cinnamic and benzoic acids,cinnamaldehydes, benzaldehyde, and anthraquinone derivatives are generalized.
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References

SHOWING 1-10 OF 12 REFERENCES
Re-investigation of the Anthraquinone Pool of Rhamnus spp.: Madagascin from the Fruits of Rhamnus cathartica and R. intermedia
TLDR
The extraction and HPLC separation of madagascin (3-isopentenyloxyemodin) from the fruits of R. cathartica L. and R. intermedia Steud.
Phytochemistry and pharmacognosy of naturally occurring prenyloxyanthraquinones.
TLDR
This review article will focus on the phytochemistry and pharmacognosy of prenyloxyanthraquinones putting in evidence the natural sources and their biological properties as anti-microbial and anticancer agents.
6-Geranyloxy-3-methyl-1,8-dihydroxyanthrone, a novel antileukemic agent fromPsorospermum febrifugum Sprach var.ferrugineum (Hook. fil)
TLDR
A systematic fractionation of the root extract ofPsorospermum febrifugum was carried out in an attempt to reisolate the antitumor xanthone psorospermin and related compounds for further structural work and testing and led to the isolation of 6-geranyloxy-3-methyl-1,8-dihydroxyanthrone.
Screening for oxyprenylated anthraquinones in Mediterranean Rhamnus species
TLDR
3- geranyloxyemodin was revealed only in one species, namely R. saxatilis, exclusively in its glycosidated form, being the recorded total content in this plant 7.37 µg/g.
An Evaluation of the Biological and Toxicological Properties of Aloe Barbadensis (Miller), Aloe Vera
  • M. Boudreau, F. Beland
  • Medicine
    Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews
  • 2006
TLDR
A review of the botany, physical and chemical properties, and biological activities of the Aloe vera plant finds that it contains multiple constituents with potential biological and toxicological activities, yet the active components elude definition.
Evaluation of six plant species used traditionally in the treatment and control of diabetes mellitus in South Africa using in vitro methods
TLDR
Antidiabetic activity of extracts of purchased plants was evaluated using in vitro α-amylase and α-glucosidase activity, as well as islets of Langerhans excretory activity, adding evidence to the traditional use of these purchased plants in the management of the type II diabetic post-prandial hyperglycemia.
Growth inhibitory activities of oxyprenylated and non-prenylated naturally occurring phenylpropanoids in cancer cell lines.
TLDR
Compounds 20 (4,2',4'-trihydroxychalcone), and 30 and 31 (two cinnamaldehydes) were cytostatic and able to overcome the intrinsic resistance of U373 cancer cells to pro-apoptotic stimuli.
Potential antineoplastic effects of Aloe-emodin: a comprehensive review.
TLDR
The present review summarizes the potential toxicity, molecular mechanism, pharmacokinetic characteristics, and pharmaceutical development of AE as an antineoplastic agent based on its physicochemical properties in an attempt to encourage further research on AE as a potential anti-cancer agent.
Anti-ulcer activity of leguminosae plants.
TLDR
It is concluded that plant extracts are potential sources of new anti-ulcer agents and should be considered for further research.
Antiviral activity of aloe-emodin against influenza A virus via galectin-3 up-regulation.
TLDR
Of three anthraquinone derivatives, aloe-emodin, with a lower cytotoxicity showed concentration-dependently reducing virus-induced cytopathic effect and inhibiting replication of influenza A in MDCK cells, which could control influenza infection in humans.
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