Screening for mutations of Bcl10 in leukaemia.


The Bcl10 gene was identified through characterization of the t(1;14)(p22;q32) associated with mucosa-associated lymphoid tissue (MALT) lymphoma. Bcl10 is implicated in the regulation of apoptosis and has been reported to be mutated in other subtypes of non-Hodgkin's B-cell lymphoma (B-NHL) and leukaemic cell lines, raising the possibility that its… (More)


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@article{Grimwade2000ScreeningFM, title={Screening for mutations of Bcl10 in leukaemia.}, author={David J Grimwade and Ming-Qing Du and Stephen E Langabeer and J. Rogers and E. Solomon}, journal={British journal of haematology}, year={2000}, volume={109 3}, pages={611-5} }