Screening for microdeletions of Y chromosome genes in patients undergoing intracytoplasmic sperm injection.

@article{Krausz1999ScreeningFM,
  title={Screening for microdeletions of Y chromosome genes in patients undergoing intracytoplasmic sperm injection.},
  author={C Krausz and C Bussani-Mastellone and Simona Granchi and Ken Mcelreavey and Gianfranco Scarselli and Gianni Forti},
  journal={Human reproduction},
  year={1999},
  volume={14 7},
  pages={1717-21}
}
The potential of assisted reproduction techniques to transmit genetic defects causing male infertility raises questions concerning the need for a systematic genetic screen and counselling. Deletions of the long arm of the Y chromosome are frequently associated with a failure of spermatogenesis. The search for Y specific sequences and for the gene families RNA binding motif (RBM) and deleted in azoospermia (DAZ) have been introduced in many laboratories. The incidence of Y microdeletions varies… CONTINUE READING

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Fundamentals of Male Infertility

Springer International Publishing • 2018

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