Screening for in vivo (anti)estrogenic activity of ephedrine and p-synephrine and their natural sources Ephedra sinica Stapf. (Ephedraceae) and Citrus aurantium L. (Rutaceae) in rats

@article{Arbo2008ScreeningFI,
  title={Screening for in vivo (anti)estrogenic activity of ephedrine and p-synephrine and their natural sources Ephedra sinica Stapf. (Ephedraceae) and Citrus aurantium L. (Rutaceae) in rats},
  author={Marcelo Dutra Arbo and M{\'a}rcia Toniolo Franco and Elisa Rupp Larentis and Solange Cristina Garcia and Viviane Cristina Sebben and Mirna Bainy Leal and Eliane Dallegrave and Renata Pereira Limberger},
  journal={Archives of Toxicology},
  year={2008},
  volume={83},
  pages={95-99}
}
Formulations containing Ephedra sinica Stapf. (Ephedraceae) and Citrus aurantium L. (Rutaceae) are consumed worldwide for body weight control. Considering the related adverse effects and the risk potential, the aim of this study is to evaluate the effects of the thermogenic compounds ephedrine, p-sinephrine, E. sinica and C. aurantium in the female reproductive system through the uterotrophic assay in immature female rats. The animals (n = 6–7) received E. sinica 85.5 and 855.0 mg/kg/day, C… CONTINUE READING
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